Published

  1. M. van der Graaf, M. Julià-Sapé, F.A. Howe, A. Ziegler, C. Majós, A. Moreno-Torres, M. Rijpkema, D. Acosta, K.S. Opstad, Y.M. van der Meulen, C. Arús and A. Heerschap. "MRS quality assessment in a multicentre study on MRS-based classification of brain tumours", NMR in Biomedicine 2008;21:148-158. Abstract/PDF DOI PMID 17458918

  2. H. Zhang, M. Langeslag, V. Breukels, B.G. Jenks, E.W. Roubos and W.J.J.M. Scheenen. "Calcium channel kinetics of melanotrope cells in Xenopus laevis depend on environmental stimulation", Gen Comp Endocrinol 2008;156:104-112. Abstract/PDF DOI PMID 18206885

  3. P.M. Nunes, E. Carvalho and J.G. Jones. "Elimination of glucose contamination from adipocyte glycogen extracts", Carbohydrate Research 2008;343:1486-1489. Abstract/PDF DOI PMID 18452901

  4. J.J.A. van Asten, V. Cuijpers, C. Hulsbergen-van de Kaa, C. Soede-Huijbregts, J.A. Witjes, A. Verhofstad and A. Heerschap. "High resolution magic angle spinning NMR spectroscopy for metabolic assessment of cancer presence and Gleason score in human prostate needle biopsies", Magnetic Resonance Materials in Physics, Biology and Medicine 2008;21:435-442. Abstract/PDF DOI PMID 19031091

  5. E.M.V. Cann, M. Rijpkema, A. Heerschap, A. van der Bilt, R. Koole and P.J.W. Stoelinga. "Quantitative dynamic contrast-enhanced MRI for the assessment of mandibular invasion by squamous cell carcinoma", Oral Oncology 2008;44:1147-1154. Abstract/PDF DOI PMID 18485797

  6. A. Claes, G. Gambarota, B. Hamans, O. van Tellingen, P. Wesseling, C. Maass, A. Heerschap and W. Leenders. "Magnetic resonance imaging-based detection of glial brain tumors in mice after antiangiogenic treatment", International Journal of Cancer 2008;122:1981-1986. Abstract/PDF DOI PMID 18081012

  7. A. Claes, P. Wesseling, J. Jeuken, C. Maass, A. Heerschap and W.P.J. Leenders. "Antiangiogenic compounds interfere with chemotherapy of brain tumors due to vessel normalization", Molecular Cancer Therapeutics 2008;7:71-78. Abstract/PDF DOI PMID 18187807

  8. G. Gambarota, W. Leenders, C. Maass, P. Wesseling, B. van der Kogel, O. van Tellingen and A. Heerschap. "Characterisation of tumour vasculature in mouse brain by USPIO contrast-enhanced MRI", British Journal of Cancer 2008;98:1784-1789. Abstract/PDF DOI PMID 18506183

  9. D.W.J. Klomp, J.P. Wijnen, T.W.J. Scheenen and A. Heerschap. "Efficient 1H to 31P polarization transfer on a clinical 3T MR system", Magnetic Resonance in Medicine 2008;60:1298-1305. Abstract/PDF DOI PMID 19030163

  10. J. Luts, J.-B. Poullet, J.M. Garcia-Gomez, A. Heerschap, M. Robles, J.A.K. Suykens and S.V. Huffel. "Effect of feature extraction for brain tumor classification based on short echo time 1H MR spectra", Magnetic Resonance in Medicine 2008;60:288-298. Abstract/PDF DOI PMID 18666120

  11. O.R.F. Mook, A. Jonker, A.C. Strang, A. Veltien, G. Gambarota, W.M. Frederiks, A. Heerschap and C.J.F.V. Noorden. "Noninvasive magnetic resonance imaging of the development of individual colon cancer tumors in rat liver", Biotechniques 2008;44:529-535. Abstract/PDF DOI PMID 18476817

  12. C.I.H.C. Nabuurs, D.W.J. Klomp, A. Veltien, H.E. Kan and A. Heerschap. "Localized sensitivity enhanced in vivo 13C MRS to detect glucose metabolism in the mouse brain", Magnetic Resonance in Medicine 2008;59:626-630. Abstract/PDF DOI PMID 18224699

  13. W.K.J. Renema, H.E. Kan and A. Heerschap. "Is ATP elevated in patients with GAMT deficiency?", American Journal of Neuroradiology 2008;29:214; author reply 214. PDF DOI PMID 18024580

  14. T.W.J. Scheenen, A. Heerschap and D.W.J. Klomp. "Towards 1H-MRSI of the human brain at 7T with slice-selective adiabatic refocusing pulses", Magnetic Resonance Materials in Physics, Biology and Medicine 2008;21:95-101. Abstract/PDF DOI PMID 18210177

  15. T.W.J. Scheenen, D.W.J. Klomp, J.P. Wijnen and A. Heerschap. "Short echo time 1H-MRSI of the human brain at 3T with minimal chemical shift displacement errors using adiabatic refocusing pulses", Magnetic Resonance in Medicine 2008;59:1-6. Abstract/PDF DOI PMID 17969076

  16. A. Heerschap, H.E. Kan, C.I.H.C. Nabuurs, W.K. Renema, D. Isbrandt and B. Wieringa. "In vivo magnetic resonance spectroscopy of transgenic mice with altered expression of guanidinoacetate methyltransferase and creatine kinase isoenzymes", Subcellular Biochemistry 2007;46:119-148. Abstract PMID 18652075

  17. D. Klomp, H. van Laarhoven, T. Scheenen, Y. Kamm and A. Heerschap. "Quantitative 19F MR spectroscopy at 3 T to detect heterogeneous capecitabine metabolism in human liver", NMR in Biomedicine 2007;20:485-492. Abstract/PDF DOI PMID 17131325

  18. T.W.J. Scheenen, F.J. Vergeldt, A.M. Heemskerk and H.V. As. "Intact plant magnetic resonance imaging to study dynamics in long-distance sap flow and flow-conducting surface area", Plant Physiol 2007;144:1157-1165. Abstract/PDF DOI PMID 17449653

  19. G. Gambarota, A. Veltien, D. Klomp, N.V. Alfen, R.V. Mulkern and A. Heerschap. "Magnetic resonance imaging and T2 relaxometry of human median nerve at 7 Tesla", Muscle and Nerve 2007;36:368-373. Abstract/PDF DOI PMID 17587225

  20. S.W.T.P.J. Heijmink, T.W.J. Scheenen, J.J. Fütterer, D.W.J. Klomp, R.A.M. Heesakkers, C.A.H. van de Kaa, E.N.J.T. van Lin, A. Heerschap and J.O. Barentsz. "Prostate and lymph node proton magnetic resonance (MR) spectroscopic imaging with external array coils at 3 T to detect recurrent prostate cancer after radiation therapy", Investigative Radiology 2007;42:420-427. Abstract/PDF DOI PMID 17507814

  21. C.R. Hooijmans, F. Rutters, P.J. Dederen, G. Gambarota, A. Veltien, T. van Groen, L.M. Broersen, D. Lütjohann, A. Heerschap, H. Tanila and A.J. Kiliaan. "Changes in cerebral blood volume and amyloid pathology in aged Alzheimer APP/PS1 mice on a docosahexaenoic acid (DHA) diet or cholesterol enriched Typical Western Diet (TWD)", Neurobiology of Disease 2007;28:16-29. Abstract/PDF DOI PMID 17720508

  22. H.E. Kan, E. Meeuwissen, J.J. van Asten, A. Veltien, D. Isbrandt and A. Heerschap. "Creatine uptake in brain and skeletal muscle of mice lacking guanidinoacetate methyltransferase assessed by magnetic resonance spectroscopy", Journal of Applied Physiology 2007;102:2121-2127. Abstract/PDF DOI PMID 17347380

  23. H.W.M. van Laarhoven, D.W.J. Klomp, M. Rijpkema, Y.L.M. Kamm, D.J.T. Wagener, J.O. Barentsz, C.J.A. Punt and A. Heerschap. "Prediction of chemotherapeutic response of colorectal liver metastases with dynamic gadolinium-DTPA-enhanced MRI and localized 19F MRS pharmacokinetic studies of 5-fluorouracil", NMR in Biomedicine 2007;20:128-140. Abstract/PDF DOI PMID 17006886

  24. J. Luts, A. Heerschap, J.A.K. Suykens and S.V. Huffel. "A combined MRI and MRSI based multiclass system for brain tumour recognition using LS-SVMs with class probabilities and feature selection", Artificial Intelligence in Medicine 2007;40:87-102. Abstract/PDF DOI PMID 17466495

  25. W.K.J. Renema, H.E. Kan, B. Wieringa and A. Heerschap. "In vivo magnetic resonance spectroscopy of transgenic mouse models with altered high-energy phosphoryl transfer metabolism", NMR in Biomedicine 2007;20:448-467. Abstract/PDF DOI PMID 17274105

  26. T.W.J. Scheenen, S.W.T.P.J. Heijmink, S.A. Roell, C.A. Hulsbergen-Van de Kaa, B.C. Knipscheer, J.A. Witjes, J.O. Barentsz and A. Heerschap. "Three-dimensional proton MR spectroscopy of human prostate at 3 T without endorectal coil: feasibility", Radiology 2007;245:507-516. Abstract/PDF DOI PMID 17848681

  27. P. Verdijk, T.W.J. Scheenen, W.J. Lesterhuis, G. Gambarota, A.A. Veltien, P. Walczak, N.M. Scharenborg, J.W.M. Bulte, C.J.A. Punt, A. Heerschap, C.G. Figdor and I.J.M. de Vries. "Sensitivity of magnetic resonance imaging of dendritic cells for in vivo tracking of cellular cancer vaccines", International Journal of Cancer 2007;120:978-984. Abstract/PDF DOI PMID 17163419

  28. M.D. Vos, T. Laudadio, A.W. Simonetti, A. Heerschap and S.V. Huffel. "Fast nosologic imaging of the brain", Journal of Magnetic Resonance 2007;184:292-301. Abstract/PDF DOI PMID 17118683

  29. J.J. Fütterer, T.W.J. Scheenen, S.W.T.P.J. Heijmink, H.J. Huisman, C.A.H.-V. de Kaa, J.A. Witjes, A. Heerschap and J.O. Barentsz. "Standardized threshold approach using three-dimensional proton magnetic resonance spectroscopic imaging in prostate cancer localization of the entire prostate", Investigative Radiology 2007;42:116-122. Abstract/PDF DOI PMID 17220729

  30. S.W.T.P.J. Heijmink, J.J. Fütterer, T. Hambrock, S. Takahashi, T.W.J. Scheenen, H.J. Huisman, C.A. Hulsbergen-Van de Kaa, B.C. Knipscheer, L.A.L.M. Kiemeney, J.A. Witjes and J.O. Barentsz. "Prostate cancer: body-array versus endorectal coil MR imaging at 3 T--comparison of image quality, localization, and staging performance", Radiology 2007;244:184-195. Abstract/PDF DOI PMID 17495178

  31. E.J. Abbink, J. De Graaf, J.H. De Haan, A. Heerschap, A.F. Stalenhoef and C.J. Tack. "Effects of pioglitazone in familial combined hyperlipidaemia", Journal of Internal Medicine 2006;259:107-116. Abstract/PDF DOI PMID 16336518

  32. F. Arias-Mendoza, G.S. Payne, K.L. Zakian, A.J. Schwarz, M. Stubbs, R. Stoyanova, D. Ballon, F.A. Howe, J.A. Koutcher, M.O. Leach, J.R. Griffiths, A. Heerschap, J.D. Glickson, S.J. Nelson, J.L. Evelhoch, H.C. Charles and T.R. Brown. "In vivo 31P MR spectral patterns and reproducibility in cancer patients studied in a multi-institutional trial", NMR in Biomedicine 2006;19:504-512. Abstract/PDF DOI PMID 16763965

  33. G. Gambarota, H.W.M. van Laarhoven, M. Philippens, J. Lok, A. van der Kogel, C.J.A. Punt and A. Heerschap. "Assessment of absolute blood volume in carcinoma by USPIO contrast-enhanced MRI", Magnetic Resonance Imaging 2006;24:279-286. Abstract/PDF DOI PMID 16563957

  34. B.C. Hamans, M. Barth, W.P. Leenders and A. Heerschap. "Contrast enhanced susceptibility weighted imaging (CE-SWI) of the mouse brain using ultrasmall superparamagnetic ironoxide particles (USPIO)", Zeitschrift für Medizinische Physik 2006;16:269-274. Abstract/PDF DOI PMID 17216752

  35. E.M. Kemper, W. Leenders, B. Küsters, S. Lyons, T. Buckle, A. Heerschap, W. Boogerd, J.H. Beijnen and O. van Tellingen. "Development of luciferase tagged brain tumour models in mice for chemotherapy intervention studies", European Journal of Cancer 2006;42:3294-3303. Abstract/PDF DOI PMID 17027258

  36. H.W.M. van Laarhoven, G. Gambarota, A. Heerschap, J. Lok, I. Verhagen, A. Corti, S. Toma, C. Gallo Stampino, A. van der Kogel and C.J.A. Punt. "Effects of the tumor vasculature targeting agent NGR-TNF on the tumor microenvironment in murine lymphomas", Invest New Drugs 2006;24:27-36. Abstract/PDF DOI PMID 16379040

  37. H.W.M. van Laarhoven, G. Gambarota, J. Lok, M. Lammens, Y.L.M. Kamm, T. Wagener, C.J.A. Punt, A.J. van der Kogel and A. Heerschap. "Carbogen breathing differentially enhances blood plasma volume and 5-fluorouracil uptake in two murine colon tumor models with a distinct vascular structure", Neoplasia 2006;8:477-487. Abstract/PDF DOI PMID 16820094

  38. H.W.M. van Laarhoven, J.H.A.M. Kaanders, J. Lok, W.J.M. Peeters, P.F.J.W. Rijken, B. Wiering, T.J.M. Ruers, C.J.A. Punt, A. Heerschap and A.J. van der Kogel. "Hypoxia in relation to vasculature and proliferation in liver metastases in patients with colorectal cancer", International Journal of Radiation Oncology, Biology, Physics 2006;64:473-482. Abstract/PDF DOI PMID 16242253

  39. H.E. Kan, M. van der Graaf, D.W.J. Klomp, M.H.M. Vlak, G.W. Padberg and A. Heerschap. "Intake of 13C-4 creatine enables simultaneous assessment of creatine and phosphocreatine pools in human skeletal muscle by 13C MR spectroscopy", Magnetic Resonance in Medicine 2006;56:953-957. Abstract/PDF DOI PMID 17036281

  40. D.W.J. Klomp, W.K.J. Renema, M. van der Graaf, B.E. de Galan, A.P.M. Kentgens and A. Heerschap. "Sensitivity-enhanced 13C MR spectroscopy of the human brain at 3 Tesla", Magnetic Resonance in Medicine 2006;55:271-278. Abstract/PDF DOI PMID 16372278

  41. A.R. Tate, J. Underwood, D.M. Acosta, M. Julia-Sapé, C. Majós, A. Moreno-Torres, F.A. Howe, M. van der Graaf, V. Lefournier, M.M. Murphy, A. Loosemore, C. Ladroue, P. Wesseling, J. Luc Bosson, M.E. Cabañas, A.W. Simonetti, W. Gajewicz, J. Calvar, A. Capdevila, P.R. Wilkins, B.A. Bell, C. Rémy, A. Heerschap, D. Watson, J.R. Griffiths and C. Arús. "Development of a decision support system for diagnosis and grading of brain tumours using in vivo magnetic resonance single voxel spectra", NMR in Biomedicine 2006;19:411-434. Abstract/PDF DOI PMID 16763971

  42. W.M. Klein, Y. van der Graaf, J. Seegers, J.H. Spithoven, E. Buskens, J.G. van Baal, J. Buth, F.L. Moll, T.T.C. Overtoom, M.R.H.M. van Sambeek and W.P.T.M. Mali. "Dutch iliac stent trial: long-term results in patients randomized for primary or selective stent placement", Radiology 2006;238:734-744. Abstract DOI PMID 16371580

  43. R.A.M. Heesakkers, J.J. Fütterer, A.M. Hövels, H.C.M. van den Bosch, T.W.J. Scheenen, Y.L. Hoogeveen and J.O. Barentsz. "Prostate cancer evaluated with ferumoxtran-10-enhanced T2*-weighted MR Imaging at 1.5 and 3.0 T: early experience", Radiology 2006;239:481-487. Abstract/PDF DOI PMID 16641354

  44. J.J. Fütterer, S.W.T.P.J. Heijmink, T.W.J. Scheenen, J. Veltman, H.J. Huisman, P. Vos, C.A. Hulsbergen-van de Kaa, J.A. Witjes, P.F.M. Krabbe, A. Heerschap and J.O. Barentsz. "Prostate cancer localization with dynamic contrast-enhanced MR imaging and proton MR spectroscopic imaging", Radiology 2006;241:449-458. Abstract/PDF DOI PMID 16966484

  45. E.N.J.T. van Lin, J.J. Fütterer, S.W.T.P.J. Heijmink, L.P. van der Vight, A.L. Hoffmann, P. van Kollenburg, H.J. Huisman, T.W.J. Scheenen, J.A. Witjes, J.W. Leer, J.O. Barentsz and A.G. Visser. "IMRT boost dose planning on dominant intraprostatic lesions: gold marker-based three-dimensional fusion of CT with dynamic contrast-enhanced and 1H-spectroscopic MRI", International Journal of Radiation Oncology, Biology, Physics 2006;65:291-303. Abstract/PDF DOI PMID 16618584

  46. H.E. Kan, T.E. Buse-Pot, R. Peco, D. Isbrandt, A. Heerschap and A. de Haan. "Lower force and impaired performance during high-intensity electrical stimulation in skeletal muscle of GAMT-deficient knockout mice", American Journal of Physiology: Cell Physiology 2005;289:C113-C119. Abstract/PDF DOI PMID 15743892

  47. H.W.M. van Laarhoven, J. Bussink, J. Lok, I. Verhagen, C.J.A. Punt, A. Heerschap, J.H.A.M. Kaanders and A.J. van der Kogel. "Modulation of hypoxia in murine liver metastases of colon carcinoma by nicotinamide and carbogen", Radiation Research 2005;164:245-249. Abstract/PDF DOI PMID 16137196

  48. H.W.M. van Laarhoven, C.J.A. Punt, Y.J.L. Kamm and A. Heerschap. "Monitoring fluoropyrimidine metabolism in solid tumors with in vivo (19)F magnetic resonance spectroscopy", Critical Reviews in Oncology/Hematology 2005;56:321-343. Abstract/PDF DOI PMID 15982898

  49. M.J.M. Serlie, J.H. de Haan, C.J. Tack, H.J. Verberne, M.T. Ackermans, A. Heerschap and H.P. Sauerwein. "Glycogen synthesis in human gastrocnemius muscle is not representative of whole-body muscle glycogen synthesis", Diabetes 2005;54:1277-1282. Abstract/PDF DOI PMID 15855310

  50. A.W. Simonetti, W.J. Melssen, F. Szabo de Edelenyi, J.J.A. van Asten, A. Heerschap and L.M.C. Buydens. "Combination of feature-reduced MR spectroscopic and MR imaging data for improved brain tumor classification", NMR in Biomedicine 2005;18:34-43. Abstract/PDF DOI PMID 15657908

  51. H.W.M. van Laarhoven, L.-F. de Geus-Oei, B. Wiering, J. Lok, M. Rijpkema, J.H.A.M. Kaanders, P.F.M. Krabbe, T. Ruers, C.J.A. Punt, A.J. van der Kogel, W.J.G. Oyen and A. Heerschap. "Gadopentetate dimeglumine and FDG uptake in liver metastases of colorectal carcinoma as determined with MR imaging and PET", Radiology 2005;237:181-188. Abstract/PDF DOI PMID 16183932

  52. G. Gambarota, M. van der Graaf, D. Klomp, R.V. Mulkern and A. Heerschap. "Echo-time independent signal modulations using PRESS sequences: a new approach to spectral editing of strongly coupled AB spin systems", Journal of Magnetic Resonance 2005;177:299-306. Abstract/PDF DOI PMID 16169267

  53. T.W.J. Scheenen, G. Gambarota, E. Weiland, D.W.J. Klomp, J.J. Fütterer, J.O. Barentsz and A. Heerschap. "Optimal timing for in vivo 1H-MR spectroscopic imaging of the human prostate at 3T", Magnetic Resonance in Medicine 2005;53:1268-1274. Abstract/PDF DOI PMID 15906304

  54. I.J.M. de Vries, W.J. Lesterhuis, J.O. Barentsz, P. Verdijk, J.H. van Krieken, O.C. Boerman, W.J.G. Oyen, J.J. Bonenkamp, J.B. Boezeman, G.J. Adema, J.W.M. Bulte, T.W.J. Scheenen, C.J.A. Punt, A. Heerschap and C.G. Figdor. "Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy", Nature Biotechnology 2005;23:1407-1413. Abstract/PDF DOI PMID 16258544

  55. H.J. Huisman, J.J. Fütterer, E.N.J.T. van Lin, A. Welmers, T.W.J. Scheenen, J.A. van Dalen, A.G. Visser, J.A. Witjes and J.O. Barentsz. "Prostate cancer: precision of integrating functional MR imaging with radiation therapy treatment by using fiducial gold markers", Radiology 2005;236:311-317. Abstract/PDF DOI PMID 15983070

  56. Y.J.L. Kamm, A. Heerschap, E.J. van den Bergh and D.J.T. Wagener. "19F-magnetic resonance spectroscopy in patients with liver metastases of colorectal cancer treated with 5-fluorouracil", Anticancer Drugs 2004;15:229-233. Abstract/PDF URL PMID 15014355

  57. R.D. Kok, M.M. de Vries, A. Heerschap and P.P. van den Berg. "Absence of harmful effects of magnetic resonance exposure at 1.5 T in utero during the third trimester of pregnancy: a follow-up study", Magnetic Resonance Imaging 2004;22:851-854. Abstract/PDF DOI PMID 15234454

  58. M. Rijpkema, J. Schuuring, P.L. Bernsen, H.J. Bernsen, J.H.A.M. Kaanders, A.J. van der Kogel and A. Heerschap. "BOLD MRI response to hypercapnic hyperoxia in patients with meningiomas: correlation with Gadolinium-DTPA uptake rate", Magnetic Resonance Imaging 2004;22:761-767. Abstract/PDF DOI PMID 15234444

  59. F. Arias-Mendoza, K. Zakian, A. Schwartz, F.A. Howe, J.A. Koutcher, M.O. Leach, J.R. Griffiths, A. Heerschap, J.D. Glickson, S.J. Nelson, J.L. Evelhoch, H.C. Charles, T.R. Brown and C.G. o.M.R.S.A. i.C. . "Methodological standardization for a multi-institutional in vivo trial of localized 31P MR spectroscopy in human cancer research. In vitro and normal volunteer studies", NMR in Biomedicine 2004;17:382-391. Abstract/PDF DOI PMID 15386624

  60. H.W.M. van Laarhoven, J. Bussink, J. Lok, C.J.A. Punt, A. Heerschap and A.J. van Der Kogel. "Effects of nicotinamide and carbogen in different murine colon carcinomas: immunohistochemical analysis of vascular architecture and microenvironmental parameters", International Journal of Radiation Oncology, Biology, Physics 2004;60:310-321. Abstract/PDF DOI PMID 15337570

  61. W.P.J. Leenders, B. Küsters, K. Verrijp, C. Maass, P. Wesseling, A. Heerschap, D. Ruiter, A. Ryan and R. de Waal. "Antiangiogenic therapy of cerebral melanoma metastases results in sustained tumor progression via vessel co-option", Clinical Cancer Research 2004;10:6222-6230. Abstract/PDF DOI PMID 15448011

  62. R.V. Mulkern, N.-k. Chen, K. Oshio, L.P. Panych, F.J. Rybicki and G. Gambarota. "Fast spectroscopic imaging strategies for potential applications in fMRI", Magnetic Resonance Imaging 2004;22:1395-1405. Abstract/PDF DOI PMID 15707789

  63. M.E.P. Philippens, G. Gambarota, J.A. Pikkemaat, W.J.M. Peeters, A.J. van der Kogel and A. Heerschap. "Characterization of late radiation effects in the rat thoracolumbar spinal cord by MR imaging using USPIO", Magnetic Resonance Materials in Physics, Biology and Medicine 2004;17:303-312. Abstract/PDF DOI PMID 15614513

  64. E.H.M. Hartman, J.A. Pikkemaat, J.J. Van Asten, J.W.M. Vehof, A. Heerschap, W.J.G. Oyen, P.H.M. Spauwen and J.A. Jansen. "Demineralized bone matrix-induced ectopic bone formation in rats: in vivo study with follow-up by magnetic resonance imaging, magnetic resonance angiography, and dual-energy X-ray absorptiometry", Tissue Engineering 2004;10:747-754. Abstract/PDF DOI PMID 15265291

  65. G. Gambarota, A. Veltien, H. van Laarhoven, M. Philippens, A. Jonker, O.R. Mook, W.M. Frederiks and A. Heerschap. "Measurements of T1 and T2 relaxation times of colon cancer metastases in rat liver at 7 T", Magnetic Resonance Materials in Physics, Biology and Medicine 2004;17:281-287. Abstract/PDF DOI PMID 15580375

  66. A. Devos, L. Lukas, A.W. Simonetti, J.A.K. Suykens, L. Vanhamme, M. van der Graaf, L.M.C. Buydens, A. Heerschap and S. Van Huffel. "Does the combination of magnetic resonance imaging and spectroscopic imaging improve the classification of brain tumours?", Conference Proceedings of the IEEE Engineering in Medicine and Biology Society 2004;1:407-410. Abstract DOI PMID 17271698

  67. F.A. van Dorsten, M. van der Graaf, M.R.W. Engelbrecht, G.J.L.H. van Leenders, A. Verhofstad, M. Rijpkema, J.J.M.C.H. de la Rosette, J.O. Barentsz and A. Heerschap. "Combined quantitative dynamic contrast-enhanced MR imaging and (1)H MR spectroscopic imaging of human prostate cancer", Journal of Magnetic Resonance Imaging 2004;20:279-287. Abstract/PDF DOI PMID 15269954

  68. M. van der Graaf, S.W.J. Janssen, J.J.A. van Asten, A.R.M.M. Hermus, C.G.J. Sweep, J.A. Pikkemaat, G.J.M. Martens and A. Heerschap. "Metabolic profile of the hippocampus of Zucker Diabetic Fatty rats assessed by in vivo 1H magnetic resonance spectroscopy", NMR in Biomedicine 2004;17:405-410. Abstract/PDF DOI PMID 15386626

  69. A. Heerschap, M.G. Sommers, H.J.A. in 't Zandt, W.K.J. Renema, A.A. Veltien and D.W.J. Klomp. "Nuclear magnetic resonance in laboratory animals", Methods Enzymol 2004;385:41-63. DOI PMID 15130732

  70. H.E. Kan, W.K.J. Renema, D. Isbrandt and A. Heerschap. "Phosphorylated guanidinoacetate partly compensates for the lack of phosphocreatine in skeletal muscle of mice lacking guanidinoacetate methyltransferase", Journal of Physiology 2004;560:219-229. Abstract/PDF DOI PMID 15284341

  71. D.W.J. Klomp, M. van der Graaf, M.A.A.P. Willemsen, Y.M. van der Meulen, A.P.M. Kentgens and A. Heerschap. "Transmit/receive headcoil for optimal 1H MR spectroscopy of the brain in paediatric patients at 3T", Magnetic Resonance Materials in Physics, Biology and Medicine 2004;17:1-4. Abstract/PDF DOI PMID 15160296

  72. L. Lukas, A. Devos, J.A.K. Suykens, L. Vanhamme, F.A. Howe, C. Majós, A. Moreno-Torres, M. Van der Graaf, A.R. Tate, C. Arús and S. Van Huffel. "Brain tumor classification based on long echo proton MRS signals", Artificial Intelligence in Medicine 2004;31:73-89. Abstract/PDF DOI PMID 15182848

  73. A. Schmidt, B. Marescau, E.A. Boehm, W.K.J. Renema, R. Peco, A. Das, R. Steinfeld, S. Chan, J. Wallis, M. Davidoff, K. Ullrich, R. Waldschütz, A. Heerschap, P.P. De Deyn, S. Neubauer and D. Isbrandt. "Severely altered guanidino compound levels, disturbed body weight homeostasis and impaired fertility in a mouse model of guanidinoacetate N-methyltransferase (GAMT) deficiency", Human Molecular Genetics 2004;13:905-921. Abstract/PDF DOI PMID 15028668

  74. M.A.A.P. Willemsen, M. Van Der Graaf, M.S. Van Der Knaap, A. Heerschap, P.H.M.F. Van Domburg, F.J.M. Gabreëls and J.J. Rotteveel. "MR imaging and proton MR spectroscopic studies in Sj�gren-Larsson syndrome: characterization of the leukoencephalopathy", American Journal of Neuroradiology 2004;25:649-657. Abstract/PDF PMID 15090362

  75. H.J.A. in 't Zandt, W.K.J. Renema, F. Streijger, C. Jost, D.W.J. Klomp, F. Oerlemans, C.E.E.M. Van der Zee, B. Wieringa and A. Heerschap. "Cerebral creatine kinase deficiency influences metabolite levels and morphology in the mouse brain: a quantitative in vivo 1H and 31P magnetic resonance study", Journal of Neurochemistry 2004;90:1321-1330. Abstract/PDF DOI PMID 15341516

  76. T.W.J. Scheenen, D.W.J. Klomp, S.A. Röll, J.J. Fütterer, J.O. Barentsz and A. Heerschap. "Fast acquisition-weighted three-dimensional proton MR spectroscopic imaging of the human prostate", Magnetic Resonance in Medicine 2004;52:80-88. Abstract/PDF DOI PMID 15236370

  77. J.J. Fütterer, T.W.J. Scheenen, H.J. Huisman, D.W.J. Klomp, F.A. van Dorsten, C.A. Hulsbergen-van de Kaa, J.A. Witjes, A. Heerschap and J.O. Barentsz. "Initial experience of 3 tesla endorectal coil magnetic resonance imaging and 1H-spectroscopic imaging of the prostate", Investigative Radiology 2004;39:671-680. Abstract/PDF PMID 15486528

  78. B.E. Cairns, G. Gambarota, P.S. Dunning, R.V. Mulkern and C.B. Berde. "Activation of peripheral excitatory amino acid receptors decreases the duration of local anesthesia", Anesthesiology 2003;98:521-529. Abstract/PDF URL PMID 12552214

  79. J.H. de Haan, D.W.J. Klomp, C.J. Tack and A. Heerschap. "Optimized detection of changes in glucose-6-phosphate levels in human skeletal muscle by 31P MR spectroscopy", Magnetic Resonance in Medicine 2003;50:1302-1306. Abstract/PDF DOI PMID 14648579

  80. A. Heerschap, R.D. Kok and P.P. van den Berg. "Antenatal proton MR spectroscopy of the human brain in vivo", Childs Nerv Syst 2003;19:418-421. Abstract/PDF DOI PMID 12811484

  81. B. Küsters, R.M.W. de Waal, P. Wesseling, K. Verrijp, C. Maass, A. Heerschap, J.O. Barentsz, F. Sweep, D.J. Ruiter and W.P.J. Leenders. "Differential effects of vascular endothelial growth factor A isoforms in a mouse brain metastasis model of human melanoma", Cancer Research 2003;63:5408-5413. Abstract/PDF URL PMID 14500375

  82. Y.J.L. Kamm, G.J. Peters, W.E. Hull, C.J.A. Punt and A. Heerschap. "Correlation between 5-fluorouracil metabolism and treatment response in two variants of C26 murine colon carcinoma", British Journal of Cancer 2003;89:754-762. Abstract/PDF DOI PMID 12915890

  83. D.W.J. Klomp, H.W.M. Van Laarhoven, A.P.M. Kentgens and A. Heerschap. "Optimization of localized 19F magnetic resonance spectroscopy for the detection of fluorinated drugs in the human liver", Magnetic Resonance in Medicine 2003;50:303-308. Abstract/PDF DOI PMID 12876706

  84. R.D. Kok, R.P.M. Steegers-Theunissen, T.K.A.B. Eskes, A. Heerschap and P.P. van den Berg. "Decreased relative brain tissue levels of inositol in fetal hydrocephalus", American Journal of Obstetrics and Gynecology 2003;188:978-980. Abstract/PDF DOI PMID 12712096

  85. H.W.M. van Laarhoven, D.W.J. Klomp, Y.J.L. Kamm, C.J.A. Punt and A. Heerschap. "In vivo monitoring of capecitabine metabolism in human liver by 19fluorine magnetic resonance spectroscopy at 1.5 and 3 Tesla field strength", Cancer Research 2003;63:7609-7612. Abstract/PDF URL PMID 14633676

  86. H.W.M. van Laarhoven, M. Rijpkema, C.J.A. Punt, T.J. Ruers, J.C.M. Hendriks, J.O. Barentsz and A. Heerschap. "Method for quantitation of dynamic MRI contrast agent uptake in colorectal liver metastases", Journal of Magnetic Resonance Imaging 2003;18:315-320. Abstract/PDF DOI PMID 12938126

  87. W. Leenders, B. Küsters, J. Pikkemaat, P. Wesseling, D. Ruiter, A. Heerschap, J. Barentsz and R.M.W. de Waal. "Vascular endothelial growth factor-A determines detectability of experimental melanoma brain metastasis in GD-DTPA-enhanced MRI", International Journal of Cancer 2003;105:437-443. Abstract/PDF DOI PMID 12712432

  88. S.P. Robinson, P.F.J.W. Rijken, F.A. Howe, P.M.J. McSheehy, B.P.J. van der Sanden, A. Heerschap, M. Stubbs, A.J. van der Kogel and J.R. Griffiths. "Tumor vascular architecture and function evaluated by non-invasive susceptibility MRI methods and immunohistochemistry", Journal of Magnetic Resonance Imaging 2003;17:445-454. Abstract/PDF DOI PMID 12655584

  89. A.-M. Van Cappellen Van Walsum, M. Rijpkema, A. Heerschap, B. Oeseburg, J.G. Nijhuis and H.W. Jongsma. "Cerebral (31)P magnetic resonance spectroscopy and systemic acid-base balance during hypoxia in fetal sheep", Pediatric Research 2003;54:747-752. Abstract/PDF DOI PMID 12904591

  90. W.K.J. Renema, D.W.J. Klomp, M.E.P. Philippens, A.J. van den Bergh, B. Wieringa and A. Heerschap. "Magnetization transfer effect on the creatine methyl resonance studied by CW off-resonance irradiation in human skeletal muscle on a clinical MR system", Magnetic Resonance in Medicine 2003;50:468-473. Abstract/PDF DOI PMID 12939753

  91. W.K.J. Renema, A. Schmidt, J.J.A. van Asten, F. Oerlemans, K. Ullrich, B. Wieringa, D. Isbrandt and A. Heerschap. "MR spectroscopy of muscle and brain in guanidinoacetate methyltransferase (GAMT)-deficient mice: validation of an animal model to study creatine deficiency", Magnetic Resonance in Medicine 2003;50:936-943. Abstract/PDF DOI PMID 14587004

  92. M. Rijpkema, J. Schuuring, Y. van der Meulen, M. van der Graaf, H. Bernsen, R. Boerman, A. van der Kogel and A. Heerschap. "Characterization of oligodendrogliomas using short echo time 1H MR spectroscopic imaging", NMR in Biomedicine 2003;16:12-18. Abstract/PDF DOI PMID 12577293

  93. A.W. Simonetti, W.J. Melssen, M. van der Graaf, G.J. Postma, A. Heerschap and L.M.C. Buydens. "A chemometric approach for brain tumor classification using magnetic resonance imaging and spectroscopy", Analytical Chemistry 2003;75:5352-5361. Abstract PMID 14710812

  94. H. Witjes, M. Rijpkema, M. van der Graaf, W. Melssen, A. Heerschap and L. Buydens. "Multispectral magnetic resonance image analysis using principal component and linear discriminant analysis", Journal of Magnetic Resonance Imaging 2003;17:261-269. Abstract/PDF DOI PMID 12541234

  95. H.J.A. in 't Zandt, A.J.C. de Groof, W.K.J. Renema, F.T.J.J. Oerlemans, D.W.J. Klomp, B. Wieringa and A. Heerschap. "Presence of (phospho)creatine in developing and adult skeletal muscle of mice without mitochondrial and cytosolic muscle creatine kinase isoforms", Journal of Physiology 2003;548:847-858. Abstract/PDF DOI PMID 12640020

  96. E.H.M. Hartman, J.A. Pikkemaat, J.W.M. Vehof, A. Heerschap, J.A. Jansen and P.H.M. Spauwen. "In vivo magnetic resonance imaging explorative study of ectopic bone formation in the rat", Tissue Engineering 2002;8:1029-1036. Abstract/PDF DOI PMID 12542948

  97. C.J. Houtman, A. Heerschap, M.J. Zwarts and D.F. Stegeman. "An additional phase in PCr use during sustained isometric exercise at 30% MVC in the tibialis anterior muscle", NMR in Biomedicine 2002;15:270-277. Abstract/PDF DOI PMID 12112609

  98. C.R. Jost, C.E.E.M. Van Der Zee, H.J.A. In 't Zandt, F. Oerlemans, M. Verheij, F. Streijger, J. Fransen, A. Heerschap, A.R. Cools and B. Wieringa. "Creatine kinase B-driven energy transfer in the brain is important for habituation and spatial learning behaviour, mossy fibre field size and determination of seizure susceptibility", European Journal of Neuroscience 2002;15:1692-1706. Abstract/PDF DOI PMID 12059977

  99. R.D. Kok, P.P. van den Berg, A.J. van den Bergh, R. Nijland and A. Heerschap. "Maturation of the human fetal brain as observed by 1H MR spectroscopy", Magnetic Resonance in Medicine 2002;48:611-616. Abstract/PDF DOI PMID 12353277

  100. R.D. Kok, P.P. van den Berg, A.J. van den Bergh, R. Nijland and A. Heerschap. "MR spectroscopy in the human fetus", Radiology 2002;223:584; author reply 584-584; autho. PDF DOI PMID 11997574

  101. R.J. Legtenberg, R.J.F. Houston, A. Heerschap, B. Oeseburg and P. Smits. "Glibenclamide attenuates ischemia-induced acidosis and loss of cardiac function in rats", European Journal of Pharmacology 2002;434:35-42. Abstract/PDF DOI PMID 11755163

  102. M. Rijpkema, J.H.A.M. Kaanders, F.B.M. Joosten, A.J. van der Kogel and A. Heerschap. "Effects of breathing a hyperoxic hypercapnic gas mixture on blood oxygenation and vascularity of head-and-neck tumors as measured by magnetic resonance imaging", International Journal of Radiation Oncology, Biology, Physics 2002;53:1185-1191. Abstract/PDF DOI PMID 12128119

  103. J. Schuuring, M. Rijpkema, H. Bernsen, P. Bernsen, R. van der Maazen, J. Kaanders, A. van der Kogel and A. Heerschap. "Effect of breathing a hyperoxic hypercapnic gas mixture on the oxygenation of meningiomas; preliminary results", Journal of Neurooncology 2002;57:127-132. Abstract/PDF DOI PMID 12125973

  104. A. Shukla-Dave, H. Poptani, L.A. Loevner, A. Mancuso, H. Serrai, D.I. Rosenthal, A.M. Kilger, D.S. Nelson, K.L. Zakian, F. Arias-Mendoza, M. Rijpkema, J.A. Koutcher, T.R. Brown, A. Heerschap and J.D. Glickson. "Prediction of treatment response of head and neck cancers with P-31 MR spectroscopy from pretreatment relative phosphomonoester levels", Academic Radiology 2002;9:688-694. Abstract/PDF DOI PMID 12061743

  105. M. Verhoye, B.P.J. van der Sanden, P.F.J.W. Rijken, H.P.W. Peters, A.J. Van der Kogel, G. Pée, G. Vanhoutte, A. Heerschap and A. Van der Linden. "Assessment of the neovascular permeability in glioma xenografts by dynamic T(1) MRI with Gadomer-17", Magnetic Resonance in Medicine 2002;47:305-313. Abstract/PDF DOI PMID 11810674

  106. T. Scheenen, A. Heemskerk, A. de Jager, F. Vergeldt and H.V. As. "Functional imaging of plants: a nuclear magnetic resonance study of a cucumber plant", Biophysical Journal 2002;82:481-492. Abstract/PDF DOI PMID 11751335

  107. C.J. Houtman, A. Heerschap, M.J. Zwarts and D.F. Stegeman. "pH heterogeneity in tibial anterior muscle during isometric activity studied by (31)P-NMR spectroscopy", Journal of Applied Physiology 2001;91:191-200. Abstract/PDF URL PMID 11408430

  108. D.W. Klomp, D.J. Collins, H.J. van den Boogert, A. Schwarz, M. Rijpkema, T. Prock, G.S. Payne, M.O. Leach and A. Heerschap. "Radio-frequency probe for 1H decoupled 31P MRS of the head and neck region", Magnetic Resonance Imaging 2001;19:755-759. Abstract/PDF DOI PMID 11672635

  109. R.D. Kok, A.J. van den Bergh, A. Heerschap, R. Nijland and P.P. van den Berg. "Metabolic information from the human fetal brain obtained with proton magnetic resonance spectroscopy", American Journal of Obstetrics and Gynecology 2001;185:1011-1015. Abstract/PDF DOI PMID 11717623

  110. P. van Luijk, H.P. Bijl, R.P. Coppes, A.J. van der Kogel, A.W. Konings, J.A. Pikkemaat and J.M. Schippers. "Techniques for precision irradiation of the lateral half of the rat cervical spinal cord using 150 MeV protons [corrected]", Physics in Medicine and Biology 2001;46:2857-2871. Abstract/PDF DOI PMID 11720351

  111. M.A. Willemsen, M.A. Lutt, P.M. Steijlen, J.R. Cruysberg, M. van der Graaf, M.W. Nijhuis-van der Sanden, J.W. Pasman, E. Mayatepek and J.J. Rotteveel. "Clinical and biochemical effects of zileuton in patients with the Sjögren-Larsson syndrome", European Journal of Pediatrics 2001;160:711-717. Abstract/PDF PMID 11795678

  112. H. in 't Zandt, M. van Der Graaf and A. Heerschap. "Common processing of in vivo MR spectra", NMR in Biomedicine 2001;14:224-232. Abstract/PDF PMID 11410940

  113. T.W. Scheenen, F.J. Vergeldt, C.W. Windt, P.A. de Jager and H.V. As. "Microscopic imaging of slow flow and diffusion: a pulsed field gradient stimulated echo sequence combined with turbo spin echo imaging", Journal of Magnetic Resonance 2001;151:94-100. Abstract/PDF DOI PMID 11444942

  114. U. Tallarek, T.W. Scheenen, P.A. de Jager and H.V. As. "Using NMR displacement imaging to characterize electroosmotic flow in porous media", Magnetic Resonance Imaging 2001;19:453-456. Abstract/PDF PMID 11445329

  115. H.J. in 't Zandt, D.W. Klomp, F. Oerlemans, B. Wieringa, C.W. Hilbers and A. Heerschap. "Proton MR spectroscopy of wild-type and creatine kinase deficient mouse skeletal muscle: dipole-dipole coupling effects and post-mortem changes", Magnetic Resonance in Medicine 2000;43:517-524. Abstract/PDF DOI PMID 10748426

  116. R.J. Gillies, Z.M. Bhujwalla, J. Evelhoch, M. Garwood, M. Neeman, S.P. Robinson, C.H. Sotak and B. Van Der Sanden. "Applications of magnetic resonance in model systems: tumor biology and physiology", Neoplasia 2000;2:139-151. Abstract/PDF URL PMID 10933073

  117. E. Janssen, P.P. Dzeja, F. Oerlemans, A.W. Simonetti, A. Heerschap, A. de Haan, P.S. Rush, R.R. Terjung, B. Wieringa and A. Terzic. "Adenylate kinase 1 gene deletion disrupts muscle energetic economy despite metabolic rearrangement", EMBO J 2000;19:6371-6381. Abstract/PDF DOI PMID 11101510

  118. Y.J. Kamm, A. Heerschap and D.J. Wagener. "Effect of carbogen breathing on the pharmacodynamics of 5-fluorouracil in a murine colon carcinoma", European Journal of Cancer 2000;36:1180-1186. Abstract/PDF DOI PMID 10854952

  119. B.P. van der Sanden, T.H. Rozijn, P.F. Rijken, H.P. Peters, A. Heerschap, A.J. van der Kogel and W.M. Bovée. "Noninvasive assessment of the functional neovasculature in 9L-glioma growing in rat brain by dynamic 1H magnetic resonance imaging of gadolinium uptake", Journal of Cerebral Blood Flow and Metabolism 2000;20:861-870. Abstract/PDF DOI PMID 10826537

  120. A.J. Schwarz, M. Rijpkema, D.J. Collins, G.S. Payne, T. Prock, A.C. Woodward, A. Heerschap and M.O. Leach. "SAR and tissue heating with a clinical (31)P MRS protocol using surface coils, adiabatic pulses, and proton-decoupling", Magnetic Resonance in Medicine 2000;44:692-700. Abstract/PDF DOI PMID 11064403

  121. A.J. Van Den Bergh, C.J. Tack, H.J. Van Den Boogert, G. Vervoort, P. Smits and A. Heerschap. "Assessment of human muscle glycogen synthesis and total glucose content by in vivo 13C MRS", European Journal of Clinical Investigation 2000;30:122-128. Abstract/PDF DOI PMID 10651836

  122. M.A. Willemsen, J.J. Rotteveel, P.M. Steijlen, A. Heerschap and E. Mayatepek. "5-Lipoxygenase inhibition: a new treatment strategy for Sjögren-Larsson syndrome", Neuropediatrics 2000;31:1-3. Abstract/PDF DOI PMID 10774987

  123. M.R. Engelbrecht, J.O. Barentsz, G.J. Jager, M. van der Graaf, A. Heerschap, J.P. Sedelaar, R.G. Aarnink and J.J. de la Rosette. "Prostate cancer staging using imaging", British Journal of Urology International 2000;86 Suppl 1:123-134. PDF PMID 10961282

  124. M. van der Graaf, R.G. Schipper, G.O. Oosterhof, J.A. Schalken, A.A. Verhofstad and A. Heerschap. "Proton MR spectroscopy of prostatic tissue focused on the detection of spermine, a possible biomarker of malignant behavior in prostate cancer", Magnetic Resonance Materials in Physics, Biology and Medicine 2000;10:153-159. Abstract PMID 10873205

  125. H. Witjes, W.J. Melssen, H.J. in 't Zandt, M. van der Graaf, A. Heerschap and L.M. Buydens. "Automatic correction for phase shifts, frequency shifts, and lineshape distortions across a series of single resonance lines in large spectral data sets", Journal of Magnetic Resonance 2000;144:35-44. Abstract/PDF DOI PMID 10783271

  126. T.W. Scheenen, D. van Dusschoten, P.A. de Jager and H.V. As. "Quantification of water transport in plants with NMR imaging", J Exp Bot 2000;51:1751-1759. Abstract/PDF PMID 11053465

  127. T.W. Scheenen, D. van Dusschoten, P.A. de Jager and H.V. As. "Microscopic displacement imaging with pulsed field gradient turbo spin-echo NMR", Journal of Magnetic Resonance 2000;142:207-215. Abstract/PDF DOI PMID 10648137

  128. Tallarek, Rapp, Scheenen, Bayer and V.A. H. "Electroosmotic and pressure-driven flow in open and packed capillaries: velocity distributions and fluid dispersion", Analytical Chemistry 2000;72:2292-2301. Abstract/PDF PMID 10845377

  129. R.A. Wevers, U.F. Engelke, S.H. Moolenaar, C. Bräutigam, J.G. de Jong, R. Duran, R.A. de Abreu and A.H. van Gennip. "1H-NMR spectroscopy of body fluids: inborn errors of purine and pyrimidine metabolism", Clinical Chemistry 1999;45:539-548. Abstract/PDF URL PMID 10102915

  130. H.J. in 't Zandt, F. Oerlemans, B. Wieringa and A. Heerschap. "Effects of ischemia on skeletal muscle energy metabolism in mice lacking creatine kinase monitored by in vivo 31P nuclear magnetic resonance spectroscopy", NMR in Biomedicine 1999;12:327-334. Abstract/PDF DOI PMID 10516614

  131. J.O. Barentsz, M. Engelbrecht, G.J. Jager, J.A. Witjes, J. de LaRosette, B.P. van Der Sanden, H.J. Huisman and A. Heerschap. "Fast dynamic gadolinium-enhanced MR imaging of urinary bladder and prostate cancer", Journal of Magnetic Resonance Imaging 1999;10:295-304. Abstract/PDF DOI PMID 10508289

  132. A.M. van Cappellen, A. Heerschap, J.G. Nijhuis, B. Oeseburg and H.W. Jongsma. "Hypoxia, the subsequent systemic metabolic acidosis, and their relationship with cerebral metabolite concentrations: An in vivo study in fetal lambs with proton magnetic resonance spectroscopy", American Journal of Obstetrics and Gynecology 1999;181:1537-1545. Abstract/PDF DOI PMID 10601940

  133. P.H. van Domburg, M.A. Willemsen, J.J. Rotteveel, J.G. de Jong, H.O. Thijssen, A. Heerschap, J.R. Cruysberg, R.J. Wanders, F.J. Gabreëls and P.M. Steijlen. "Sjögren-Larsson syndrome: clinical and MRI/MRS findings in FALDH-deficient patients", Neurology 1999;52:1345-1352. Abstract/PDF DOI PMID 10227616

  134. M. van der Graaf, H.J. van den Boogert, G.J. Jager, J.O. Barentsz and A. Heerschap. "Human prostate: multisection proton MR spectroscopic imaging with a single spin-echo sequence--preliminary experience", Radiology 1999;213:919-925. Abstract/PDF DOI PMID 10580976

  135. A. Heerschap, C. Houtman, H.J. in 't Zandt, A.J. van den Bergh and B. Wieringa. "Introduction to in vivo 31P magnetic resonance spectroscopy of (human) skeletal muscle", Proc Nutr Soc 1999;58:861-870. Abstract/PDF DOI PMID 10817153

  136. S.H. Moolenaar, J. Poggi-Bach, U.F. Engelke, J.M. Corstiaensen, A. Heerschap, J.G. de Jong, B.A. Binzak, J. Vockley and R.A. Wevers. "Defect in dimethylglycine dehydrogenase, a new inborn error of metabolism: NMR spectroscopy study", Clinical Chemistry 1999;45:459-464. Abstract/PDF URL PMID 10102904

  137. T.H. Rozijn, B.P. van der Sanden, A. Heerschap, J.H. Creyghton and W.M. Boveé. "Determination of in vivo rat muscle Gd-DTPA relaxivity at 6.3 T", Magnetic Resonance Materials in Physics, Biology and Medicine 1999;9:65-71. Abstract/PDF DOI PMID 10555175

  138. M.E. Rubio-Gozalbo, A. Heerschap, J.M. Trijbels, L. De Meirleir, H.O. Thijssen and J.A. Smeitink. "Proton MR spectroscopy in a child with pyruvate dehydrogenase complex deficiency", Magnetic Resonance Imaging 1999;17:939-944. Abstract/PDF DOI PMID 10402601

  139. B.P. van der Sanden, H.J. in't Zandt, L. Hoofd, R.A. de Graaf, K. Nicolay, P.F. Rijken, A.J. van der Kogel and A. Heerschap. "Global HDO uptake in human glioma xenografts is related to the perfused capillary distribution", Magnetic Resonance in Medicine 1999;42:479-489. Abstract/PDF DOI PMID 10467292

  140. B.P. van der Sanden, A. Heerschap, L. Hoofd, A.W. Simonetti, K. Nicolay, A. van der Toorn, W.N. Colier and A.J. van der Kogel. "Effect of carbogen breathing on the physiological profile of human glioma xenografts", Magnetic Resonance in Medicine 1999;42:490-499. Abstract/PDF DOI PMID 10467293

  141. B.P. van der Sanden, A. Heerschap, A.W. Simonetti, P.F. Rijken, H.P. Peters, G. Stüben and A.J. van der Kogel. "Characterization and validation of noninvasive oxygen tension measurements in human glioma xenografts by 19F-MR relaxometry", International Journal of Radiation Oncology, Biology, Physics 1999;44:649-658. Abstract/PDF DOI PMID 10348296

  142. J.O. Barentsz, M.R. Engelbrecht, J.A. Witjes, J.J. de la Rosette and M. van der Graaf. "MR imaging of the male pelvis", European Radiology 1999;9:1722-1736. Abstract PMID 10602944

  143. H.J. in 't Zandt, B. Wieringa and A. Heerschap. "Creatine kinase knockout mice--what is the phenotype: skeletal muscle", Magnetic Resonance Materials in Physics, Biology and Medicine 1998;6:122-123. PDF URL PMID 9803381

  144. A.J. van den Bergh, H.J. van den Boogert and A. Heerschap. "Heteronuclear cross polarization for enhanced sensitivity of in vivo 13C MR spectroscopy on a clinical 1.5 T MR system", Journal of Magnetic Resonance 1998;135:93-98. Abstract/PDF DOI PMID 9799681

  145. A.J. van den Bergh, H.J. van den Boogert and A. Heerschap. "Calibration of the 1H decoupling field strength and experimental evaluation of the specific RF absorption rate in 1H-decoupled human 13C-MRS", Magnetic Resonance in Medicine 1998;39:642-646. Abstract/PDF DOI PMID 9543427

  146. A.M. van Cappellen van Walsum, A. Heerschap, J.G. Nijhuis, B. Oeseburg and H.W. Jongsma. "Proton magnetic resonance spectroscopy of fetal lamb brain during hypoxia", American Journal of Obstetrics and Gynecology 1998;179:756-757. Abstract/PDF DOI PMID 9757984

  147. L.F. Massuger, P.B. van Vierzen, U. Engelke, A. Heerschap and R. Wevers. "1H-magnetic resonance spectroscopy: a new technique to discriminate benign from malignant ovarian tumors", Cancer 1998;82:1726-1730. Abstract/PDF DOI PMID 9576295

  148. T.H. Rozijn, B.P. van der Sanden, A. Heerschap, J.H. Creyghton and W.M. Bovée. "Influence of the pharmacokinetic model on the quantification of the Gd-DTPA uptake rate in brain tumours using direct T1 measurements", Magnetic Resonance Materials in Physics, Biology and Medicine 1998;6:37-43. Abstract/PDF DOI PMID 9794288

  149. K. Steeghs, F. Oerlemans, A. de Haan, A. Heerschap, L. Verdoodt, M. de Bie, W. Ruitenbeek, A. Benders, C. Jost, J. van Deursen, P. Tullson, R. Terjung, P. Jap, W. Jacob, D. Pette and B. Wieringa. "Cytoarchitectural and metabolic adaptations in muscles with mitochondrial and cytosolic creatine kinase deficiencies", Mol Cell Biochem 1998;184:183-194. Abstract/PDF DOI PMID 9746321

  150. D.V. Dusschoten, U. Tallarek, T. Scheenen, U.D. Neue and H.V. As. "Spatially resolved transport properties in radially compressed bead packings studied by PFG NMR", Magnetic Resonance Imaging 1998;16:703-706. Abstract/PDF PMID 9803945

  151. W.M. Bovée, T.H. Rozijn, B.P. Van Der Sanden and A. Heerschap. "NMR perfusion and metabolic imaging and some examples on brain tumours", Cell Mol Biol (Noisy-le-grand) 1997;43:675-689. Abstract URL PMID 9298590

  152. M. van der Graaf, G.J. Jager and A. Heerschap. "Removal of the outer lines of the citrate multiplet in proton magnetic resonance spectra of the prostatic gland by accurate timing of a point-resolved spectroscopy pulse sequence", Magnetic Resonance Materials in Physics, Biology and Medicine 1997;5:65-69. Abstract/PDF DOI PMID 9219182

  153. B.P. van der Sanden, P.F. Rijken, A. Heerschap, H.J. Bernsen and A.J. van der Kogel. "In vivo (31)P magnetic resonance spectroscopy and morphometric analysis of the perfused vascular architecture of human glioma xenografts in nude mice", British Journal of Cancer 1997;75:1432-1438. Abstract/PDF DOI PMID 9166934

  154. K. Steeghs, A. Benders, F. Oerlemans, A. de Haan, A. Heerschap, W. Ruitenbeek, C. Jost, J. van Deursen, B. Perryman, D. Pette, M. Brückwilder, J. Koudijs, P. Jap, J. Veerkamp and B. Wieringa. "Altered Ca2+ responses in muscles with combined mitochondrial and cytosolic creatine kinase deficiencies", Cell 1997;89:93-103. Abstract/PDF DOI PMID 9094718

  155. K. Steeghs, A. Heerschap, A. de Haan, W. Ruitenbeek, F. Oerlemans, J. van Deursen, B. Perryman, D. Pette, M. Brückwilder, J. Koudijs, P. Jap and B. Wieringa. "Use of gene targeting for compromising energy homeostasis in neuro-muscular tissues: the role of sarcomeric mitochondrial creatine kinase", Journal of Neuroscience Methods 1997;71:29-41. Abstract/PDF DOI PMID 9125373

  156. A. Heerschap, G.J. Jager, M. van der Graaf, J.O. Barentsz and S.H. Ruijs. "Proton MR spectroscopy of the normal human prostate with an endorectal coil and a double spin-echo pulse sequence", Magnetic Resonance in Medicine 1997;37:204-213. Abstract PMID 9001144

  157. A. Heerschap, G.J. Jager, M. van der Graaf, J.O. Barentsz, J.J. de la Rosette, G.O. Oosterhof, E.T. Ruijter and S.H. Ruijs. "In vivo proton MR spectroscopy reveals altered metabolite content in malignant prostate tissue", Anticancer Research 1997;17:1455-1460. Abstract/PDF URL PMID 9179183

  158. Y.J. Kamm, A. Heerschap, G. Rosenbusch, I.M. Rietjens, J. Vervoort and D.J. Wagener. "5-Fluorouracil metabolite patterns in viable and necrotic tumor areas of murine colon carcinoma determined by 19F NMR spectroscopy", Magnetic Resonance in Medicine 1996;36:445-450. Abstract/PDF DOI PMID 8875416

  159. W.G. Negendank, R. Sauter, T.R. Brown, J.L. Evelhoch, A. Falini, E.D. Gotsis, A. Heerschap, K. Kamada, B.C. Lee, M.M. Mengeot, E. Moser, K.A. Padavic-Shaller, J.A. Sanders, T.A. Spraggins, A.E. Stillman, B. Terwey, T.J. Vogl, K. Wicklow and R.A. Zimmerman. "Proton magnetic resonance spectroscopy in patients with glial tumors: a multicenter study", Journal of Neurosurgery 1996;84:449-458. Abstract/PDF DOI PMID 8609557

  160. A.J. Van Den Bergh, S. Houtman, A. Heerschap, N.J. Rehrer, H.J. Van Den Boogert, B. Oeseburg and M.T. Hopman. "Muscle glycogen recovery after exercise during glucose and fructose intake monitored by 13C-NMR", Journal of Applied Physiology 1996;81:1495-1500. Abstract/PDF URL PMID 8904559

  161. M. van der Graaf and A. Heerschap. "Effect of Cation Binding on the Proton Chemical Shifts and the Spin-Spin Coupling Constant of Citrate", J Magn Reson B 1996;112:58-62. PMID 8661307

  162. N.G. Abeling, A.H. van Gennip, H.D. Bakker, A. Heerschap, U. Engelke and R.A. Wevers. "Diagnosis of a new case of trimethylaminuria using direct proton NMR spectroscopy of urine", Journal of Inherited Metabolic Disease 1995;18:182-184. PDF URL PMID 7564241

  163. E.B. Cornel, G.A. Smits, F.M. Debruyne, A. Heerschap, J.A. Schalken and G.O. Oosterhof. "The effects of successive high-energy shock-wave tumor administration on tumor blood flow", Ultrasound in Medicine and Biology 1995;21:243-248. Abstract/PDF DOI PMID 7571132

  164. E.B. Cornel, G.A. Smits, J.E. de Ruijter, G.O. Oosterhof, A. Heerschap, F.M. Debruyne and J.A. Schalken. "In vitro proton magnetic resonance spectroscopy of four human prostate cancer cell lines", Prostate 1995;26:275-280. Abstract/PDF DOI PMID 7753713

  165. B.A. Holshouser, M. Komu, H.E. Möller, J. Zijlmans, H. Kolem, D. Hinshaw, Jr, P. Sonninen, P. Vermathen, A. Heerschap and H. Masur. "Localized proton NMR spectroscopy in the striatum of patients with idiopathic Parkinson's disease: a multicenter pilot study", Magnetic Resonance in Medicine 1995;33:589-594. Abstract/PDF DOI PMID 7596261

  166. R.W. van der Maazen, H.O. Thijssen, J.H. Kaanders, A. de Koster, A. Keyser, M.J. Prick, J.A. Grotenhuis, P. Wesseling and A.J. van der Kogel. "Conventional radiotherapy combined with carbogen breathing and nicotinamide for malignant gliomas", Radiotherapy and Oncology 1995;35:118-122. Abstract/PDF DOI PMID 7569019

  167. R.A. Wevers, U. Engelke, U. Wendel, J.G. de Jong, F.J. Gabreëls and A. Heerschap. "Standardized method for high-resolution 1H-NMR of cerebrospinal fluid", Clinical Chemistry 1995;41:744-751. Abstract/PDF URL PMID 7729054

  168. E.B. Cornel, A. Heerschap, G.A. Smits, G.O. Oosterhof, F.M. Debruyne and J.A. Schalken. "Magnetic resonance spectroscopy detects metabolic differences between seven Dunning rat prostate tumor sublines with different biological behavior", Prostate 1994;25:19-28. Abstract DOI PMID 8022708

  169. J. van Deursen, P. Jap, A. Heerschap, H. ter Laak, W. Ruitenbeek and B. Wieringa. "Effects of the creatine analogue beta-guanidinopropionic acid on skeletal muscles of mice deficient in muscle creatine kinase", Biochimica Et Biophysica Acta 1994;1185:327-335. Abstract PMID 8180237

  170. J. van Deursen, W. Ruitenbeek, A. Heerschap, P. Jap, H. ter Laak and B. Wieringa. "Creatine kinase (CK) in skeletal muscle energy metabolism: a study of mouse mutants with graded reduction in muscle CK expression", Proceedings of the National Academy of Sciences of the United States of America 1994;91:9091-9095. Abstract/PDF URL PMID 8090775

  171. A. Heerschap and P.P. van den Berg. "Proton magnetic resonance spectroscopy of human fetal brain", American Journal of Obstetrics and Gynecology 1994;170:1150-1151. Abstract DOI PMID 8166200

  172. V.J. Kamm, I.M. Rietjens, J. Vervoort, A. Heerschap, G. Rosenbusch, H.P. Hofs and D.J. Wagener. "Effect of modulators on 5-fluorouracil metabolite patterns in murine colon carcinoma determined by in vitro 19F nuclear magnetic resonance spectroscopy", Cancer Research 1994;54:4321-4326. Abstract/PDF URL PMID 8044779

  173. G.A. Smits, E.B. Cornel, E. van de Boogert, G.O. Oosterhof, F.M. Debruyne, J.A. Schalken and A. Heerschap. "Effects of high energy shock waves on tumor blood flow and metabolism: 31P/1H/2H nuclear magnetic resonance study", NMR in Biomedicine 1994;7:319-326. Abstract DOI PMID 7718432

  174. R.A. Wevers, U. Engelke and A. Heerschap. "High-resolution 1H-NMR spectroscopy of blood plasma for metabolic studies", Clinical Chemistry 1994;40:1245-1250. Abstract/PDF URL PMID 8013094

  175. J.C. Zijlmans, A. de Koster, M.A. van 't Hof, H.O. Thijssen, M.W. Horstink and A. Heerschap. "Proton magnetic resonance spectroscopy in suspected vascular ischemic parkinsonism", Acta Neurologica Scandinavica 1994;90:405-411. Abstract/PDF DOI PMID 7892759

  176. E.B. Cornel, G.A. Smits, G.O. Oosterhof, H.F. Karthaus, F.M. Deburyne, J.A. Schalken and A. Heerschap. "Characterization of human prostate cancer, benign prostatic hyperplasia and normal prostate by in vitro 1H and 31P magnetic resonance spectroscopy", Journal of Urology 1993;150:2019-2024. Abstract PMID 7693985

  177. J. van Deursen, A. Heerschap, F. Oerlemans, W. Ruitenbeek, P. Jap, H. ter Laak and B. Wieringa. "Skeletal muscles of mice deficient in muscle creatine kinase lack burst activity", Cell 1993;74:621-631. Abstract/PDF DOI PMID 8358791

  178. A. Heerschap, J.A. den Hollander, H. Reynen and R.J. Goris. "Metabolic changes in reflex sympathetic dystrophy: a 31P NMR spectroscopy study", Muscle and Nerve 1993;16:367-373. Abstract DOI PMID 8455649

  179. G.A. Smits, P.H. Jap, A. Heerschap, G.O. Oosterhof, F.M. Debruyne and J.A. Schalken. "Biological effects of high energy shock waves in mouse skeletal muscle: correlation between 31P magnetic resonance spectroscopic and microscopic alterations", Ultrasound in Medicine and Biology 1993;19:399-409. Abstract PMID 8356784

  180. H.J. Bernsen, A. Heerschap, A.J. van der Kogel, J.J. van Vaals, M.J. Prick, E.F. Poels, J. Meyer and J.A. Grotenhuis. "Image-guided 1H NMR spectroscopical and histological characterization of a human brain tumor model in the nude rat; a new approach to monitor changes in tumor metabolism", Journal of Neurooncology 1992;13:119-130. Abstract/PDF URL PMID 1331342

  181. H.J. Bernsen, W.I. Verhagen, M.A. de Bijl and A. Heerschap. "Magnetic resonance studies on brain dysfunction induced by organic solvents", Acta Neurologica Belgica 1992;92:207-214. Abstract PMID 1441899

  182. A. Heerschap. "Current status of human in vivo NMR spectroscopy", European Journal of Radiology 1992;14:117-123. Abstract/PDF DOI PMID 1563412

  183. G.A. Smits, A. Heerschap, G.O. Oosterhof, J.H. Ruys, C.W. Hilbers, F.M. Debruyne and J.A. Schalken. "Early metabolic response to high energy shock waves in a human tumor kidney xenograft monitored by 31P magnetic resonance spectroscopy", Ultrasound in Medicine and Biology 1991;17:791-801. Abstract/PDF DOI PMID 1808797

  184. J.J. van Vaals, A.H. Bergman, H.J. van den Boogert, A. Heerschap, A.J. van der Kogel, A.C. Ruifrok and H.J. Bernsen. "Non-invasive in vivo localized 1H spectroscopy of human astrocytoma implanted in rat brain: regional differences followed in time", NMR in Biomedicine 1991;4:125-132. Abstract DOI PMID 1911099

  185. A. Heerschap, P.R. Luyten, J.I. van der Heyden, L.J. Oosterwaal and J.A. den Hollander. "Broadband proton decoupled natural abundance 13C NMR spectroscopy of humans at 1.5 T", NMR in Biomedicine 1989;2:124-132. Abstract DOI PMID 2641301

  186. P.R. Luyten, G. Bruntink, F.M. Sloff, J.W. Vermeulen, J.I. van der Heijden, J.A. den Hollander and A. Heerschap. "Broadband proton decoupling in human 31P NMR spectroscopy", NMR in Biomedicine 1989;1:177-183. Abstract DOI PMID 2641284

  187. A. Heerschap, A.H. Bergman, J.J. van Vaals, P. Wirtz, H.M. Loermans and J.H. Veerkamp. "Alterations in relative phosphocreatine concentrations in preclinical mouse muscular dystrophy revealed by in vivo NMR", NMR in Biomedicine 1988;1:27-31. Abstract DOI PMID 3275021

  188. A. Heerschap, J.J. van Vaals, A.H. Bergman, J.H. den Boef, P.H. van Gerwen and E.J. Gravenmade. "In vivo 31P NMR studies of rat salivary glands at 6.3 tesla", Magnetic Resonance in Medicine 1988;8:129-141. Abstract DOI PMID 3210951