MRI plays an increasingly important role in the diagnosis and staging of prostate cancer, with multiparametric MRI (including T2-weighted imaging, diffusion imaging, spectroscopy, and contrast-enhanced imaging) offering high accuracy for detecting and localizing tumors. Compared to other imaging techniques, MRI provides superior soft-tissue contrast and can guide biopsies and treatment decisions.
At 3T MRI, the use of an endorectal coil (ERC) significantly improves image quality, tumor localization, and staging accuracy, although it can alter prostate shape and volume, which is relevant for radiotherapy planning. Studies showed high sensitivity and specificity for detecting tumor spread, especially when interpreted by experienced radiologists.
MR spectroscopic imaging (MRSI) can detect metabolic changes in prostate cancer and differentiate tumor from healthy tissue. While feasible with external coils alone, the addition of an ERC improves diagnostic accuracy.
Overall, the thesis demonstrates that MRI—especially at 3T with an endorectal coil—enhances prostate cancer detection, localization, and staging, supporting more personalized treatment planning.