Multi-nuclear magnetic resonance spectroscopy of human brain tumours.

Glial brain tumours are rare but highly aggressive, with poor patient outcomes and no current cure. This highlights the need for better, non-invasive diagnostic tools.

This research focuses on improving Magnetic Resonance Spectroscopy (MRS), an imaging technique that measures the chemical composition of brain tissue. New and enhanced MRS methods were developed to better detect, classify, and study brain tumours—particularly gliomas—directly in patients.

Key advances include more reliable and sensitive imaging techniques, improved ability to distinguish between tumour types, and new ways to measure tumour metabolism. These methods can identify tumour infiltration and monitor how tumours process nutrients like glucose, offering deeper insight into tumour behaviour.

Overall, the findings show that advanced MRS techniques have strong potential to improve brain tumour diagnosis, personalise treatment, and support non-invasive monitoring of disease progression.